This research is a synthesis that distills out insights into research into the behaviors that influence successful collaboration. As we continue to face complex and difficult-to-solve problems such as climate change, social injustice, and a global pandemic, the need for collaboration is more pressing than ever. Multi-stakeholder partnerships (MSPs) are touted as promising mechanisms to tackle these challenges; however, despite their promise, not all partnerships are successful in their collaborative efforts. The purpose of the research presented here is to better understand collaboration in the context of MSPs.